Publicações

Todos Chemical Ecology3 Foodomics6 Natural Products7 Sem categoria1

12 jul 2021

Brazilian sunberry (Solanum oocarpum Sendtn): Alkaloid composition and improvement of mitochondrial functionality and insulin secretion of INS-1E cells

Chronic high-glucose levels induce the generation of reactive oxygen species leading to mitochondrial dysfunction, which is one of the pathological triggers in the development of diabetes. This study investigated the…

20 mar 2021

Arcopilus amazonicus (Chaetomiaceae), a new fungal species from the Amazon rainforest native plant Paullinia cupana

Arcopilus is a genus recently proposed after the taxonomic restructuring of Chaetomium with only seven described species so far. During the characterization of the microbiome of the Amazonian guarana plant (Paullinia cupana var. sorbilis), nine…

1 mar 2021

Impact of ripening on the health-promoting components from fruta-do-lobo (Solanum lycocarpum St. Hill).

Fruta-do-lobo (Solanum lycocarpum St. Hill) is an underutilized native fruit commonly found in the Brazilian Cerrado, very known due to the presence of glycoalkaloids. In this work we evaluated the biochemical changes…

28 fev 2021

Sequential high-pressure extraction to obtain capsinoids and phenolic compounds from biquinho pepper (Capsicum chinense)

This work proposes a sequential high-pressure extraction to recover bioactives from biquinho peppers. The nonpolar fraction was extracted with supercritical carbon dioxide (sc−CO2). Then, the sc−CO2 extracted biquinho pepper (EBP) was…

15 fev 2021

New Cyclodepsipeptide Derivatives Revealed by Genome Mining and Molecular Networking.

Genome mining and molecular networking analyses have revealed a renewed capacity to uncover molecules and biosynthetic pathways from bacterial secondary metabolism. The present study describes the association of genome mining…

1 fev 2021

Molecular Networking for the Target Discovery of Oxahomoaporphine and 8-Oxohomoaporphine Alkaloids from Duguetia surinamensis

In addition to seven known alkaloids (2, 6–11) and 1,2,4-trimethoxybenzene (1), three isoquinoline-derived alkaloids (3–5), namely, duguetinine (3), a compound based on an unprecedented oxahomoaporphine scaffold, and two new 8-oxohomoaporphine alkaloids,…

30 jan 2021

In vitro bioactivity approach of unripe genipap (Genipa americana L., Rubiaceae) fruit extract and its solid lipid microparticle.

Growing awareness in favor of innovative and healthier alternatives is creating a noticeable shift from synthetic colorants to natural additives. And, such a swing in the consumer market is growing…

10 jan 2021

Molecular networking-based dereplication of strictosidine-derived monoterpene indole alkaloids from the curare ingredient Strychnos peckii.

Monoterpene indole alkaloids (MIAs) are a large group of biologically active compounds produced by hundreds of plant species in numerous plant families, such as Apocynaceae, Loganiaceae and Rubiaceae. Although this…

1 jan 2021

Antifungal potential of secondary metabolites involved in the interaction between citrus pathogens.

Numerous postharvest diseases have been reported that cause substantial losses of citrus fruits worldwide. Penicillium digitatum is responsible for up to 90% of production losses, and represent a problem for worldwide economy.…

8 abr 2020

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products

The chemical space covered by natural products is immense and widely unrecognized. Therefore, convenient methodologies to perform wide-ranging evaluation of their functions in nature and potential human benefits (e.g., for…

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